Here are links to some of our research and reviews that indicate dimethicone and dimethiconol pose minimal to no environmental impact

• Ingredient Review (CIR) Panel: 
• This review assesses the safety of dimethicone, stating that it is non-toxic and does not significantly accumulate in the environment. The panel concluded that dimethicone and related silicones do not pose environmental risks when used in cosmetics. CIR Safety Review​ (CIR Safety)

• MDPI Study on Sustainable Formulations: 
• This study focuses on eco-design for cosmetic formulations and suggests that silicones like dimethicone, though not biodegradable, degrade over time into harmless substances and are largely removed by wastewater treatments. MDPI on Eco-Design and Environmental Impact​(MDPI)

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Conclusion:

Research on dimethiconol, a type of silicone used in cosmetics and personal care products, shows that it poses minimal environmental risks under certain conditions, particularly due to its poor water solubility and high molecular weight, which limits its bioavailability. This means that dimethiconol tends to stay in sediments rather than entering aquatic ecosystems significantly. Studies indicate that dimethiconol is not easily absorbed by living organisms and degrades over time into inert components such as silica, water, and carbon dioxide, minimising its long-term environmental impact. n general, studies related to dimethicone and dimethiconol's environmental behaviour focus on their low reactivity and minimal toxicity to aquatic life.

 

Here are some of our research on why high purity silicone lube are best for not disturbing your natural vaginal microflora 

• Introduction: 
• Vaginal health is a critical aspect of overall well-being for individuals, and maintaining a balanced vaginal microflora and pH is essential for preventing infections and discomfort. Recent research has shed light on the positive effects of silicone-based lubricants on vaginal health. This article delves into the intricacies of how silicone-based lubricants contribute to a healthier vaginal environment by supporting the balance of microflora and maintaining optimal pH levels.

• Understanding Vaginal Microflora and pH: 
• The vagina is home to a diverse community of microorganisms, collectively known as vaginal microflora. These microorganisms, including bacteria, yeast, and other microbes, play a crucial role in maintaining a healthy and functional vaginal environment. The pH level of the vagina, typically slightly acidic (around 3.8 to 4.5), is a key factor in regulating the growth and activity of these microorganisms.

• Challenges to Vaginal Health: 
• Various factors, such as hormonal changes, sexual activity, and the use of certain products, can disrupt the delicate balance of vaginal microflora and pH. Imbalances may lead to conditions like bacterial vaginosis or yeast infections, emphasising the importance of practices that support and maintain a healthy vaginal environment.

• Silicone-Based Lubricants and Vaginal Microflora:
• Silicone-based lubricants have gained attention for their positive impact on vaginal microflora. Unlike water-based lubricants, which may contain preservatives or additives that could disturb the natural balance, silicone-based lubricants are inert and do not foster the growth of harmful microorganisms. This quality helps in preserving the vaginal microflora and preventing disruptions.

• Biocompatibility and Non-Allergenic Properties:
• Silicone is known for its biocompatibility, making it suitable for intimate use. Silicone-based lubricants are non-allergenic, reducing the risk of irritation or allergic reactions that might disturb the vaginal microflora. This makes them an excellent option for individuals with sensitive skin or prone to allergies.

• Silicone-based lubricants are pH neutral, meaning they do not significantly alter the pH of the vagina upon application. This is crucial for individuals aiming to maintain the natural acidity of their vaginal environment. By not causing significant shifts in pH, silicone-based lubricants contribute to the preservation of the optimal conditions for the growth of beneficial microflora.

• Reduced Friction and Micro-abrasions:
• The smooth and slippery texture of silicone-based lubricants reduces friction during intimate activities. This reduction in friction is beneficial in preventing micro-abrasions or tiny tears in the vaginal tissues, which could potentially disrupt the natural balance of microflora. By minimising these abrasions, silicone lubricants support overall vaginal health.

• Clinical Studies and User Experiences: 
• Several clinical studies have explored the effects of silicone-based lubricants on vaginal health. These studies often highlight the positive outcomes, including improved comfort, reduced irritation, and maintenance of a balanced vaginal environment. User experiences also frequently report satisfaction with silicone-based lubricants in promoting vaginal well-being.

• Educational Initiatives and Awareness: 
• Promoting awareness and education about the benefits of silicone-based lubricants for vaginal health is crucial. Many individuals may not be aware of the impact of lubricant choice on the vaginal microflora and pH. Encouraging informed decision-making empowers individuals to prioritise products that align with their intimate health goals.

Conclusion:
Silicone-based lubricants play a pivotal role in supporting vaginal health by positively influencing the balance of microflora and maintaining optimal pH levels. Their biocompatibility, long-lasting lubrication, and resistance to disruption make them a valuable choice for individuals seeking to enhance their intimate well-being. As research continues to unfold, silicone-based lubricants are likely to remain a key component in promoting a healthy and balanced vaginal environment.

 

References:

Hickey, M., Marino, J.L., Braat, S. et al. A randomized, double-blind, crossover trial comparing a silicone- versus water-based lubricant for sexual discomfort after breast cancer. Breast Cancer Res Treat 158, 79–90 (2016). https://doi.org/10.1007/s10549-016-3865-1

 

The importance of maintaining a healthy vaginal microflora

• Introduction:
• The vagina is not just an anatomical structure; it is a complex ecosystem hosting a myriad of microorganisms collectively known as vaginal microflora. This unique microbial community plays a vital role in maintaining the health and functionality of the female reproductive system. This article explores the importance of vaginal microflora and delves into the diverse roles each microbe plays in ensuring the well-being of this intimate environment.

• Introduction to Vaginal Microflora:
• Vaginal microflora refers to the diverse array of microorganisms inhabiting the vagina. This community includes bacteria, fungi, and other microbes, creating a dynamic ecosystem with a delicate balance. The composition of this microflora can vary among individuals and change throughout different stages of life.

• Importance of Vaginal Microflora:
• The vaginal microflora is essential for maintaining the overall health of the female reproductive system. Its importance extends beyond preventing infections; it contributes to hormonal regulation, immune system modulation, and the prevention of harmful microorganisms from colonising the vagina.

• Roles of Lactobacilli:
• Lactobacilli are the predominant bacteria in the vaginal microflora, particularly in healthy individuals.

• These beneficial bacteria serve several crucial roles:
• Acidification of the Vaginal Environment: Lactobacilli produce lactic acid, creating an acidic environment (pH 3.8-4.5) in the vagina. This acidity inhibits the growth of pathogenic bacteria and fungi, providing a natural defence against infections.

• Production of Hydrogen Peroxide (H2O2): Some strains of lactobacilli produce hydrogen peroxide, which has antimicrobial properties. This further contributes to the prevention of infections by creating an inhospitable environment for harmful microbes.

• Maintenance of a Stable Microbial Community: Lactobacilli play a crucial role in preventing overgrowth of harmful microorganisms by maintaining a stable microbial community. Their dominance ensures a balanced and healthy vaginal environment.

• Other Bacterial Species in Vaginal Microflora:While lactobacilli are predominant, other bacterial species also contribute to the diverse ecosystem of the vaginal microflora:

• Streptococci and Staphylococci: These bacteria are found in smaller quantities and can contribute to the production of lactic acid, supporting the overall acidic environment of the vagina.

• Bacteroides and Clostridia: These anaerobic bacteria are present in low numbers and play a role in breaking down complex molecules, contributing to the nutrient availability in the vaginal environment.

• Fungi in Vaginal Microflora:Fungi, particularly Candida species, are a natural part of the vaginal microflora. However, their overgrowth can lead to conditions like yeast infections. The delicate balance between fungi and bacteria is crucial for preventing infections while allowing for the beneficial functions of fungi in the vaginal ecosystem.

• Roles of Vaginal Microflora in Hormonal Regulation:The vaginal microflora actively participates in hormonal regulation, influencing estrogen metabolism. Lactobacilli, in particular, can convert precursor compounds into bioactive estrogen, impacting hormonal balance. This interplay is essential for various reproductive processes, including menstruation and pregnancy.

• Immune System Modulation:Vaginal microflora plays a vital role in modulating the immune system. The presence of beneficial bacteria helps stimulate the local immune response, enhancing the body's ability to recognise and eliminate harmful pathogens. This immune modulation is crucial for preventing infections and maintaining overall vaginal health.

• Pregnancy and Birth Outcomes:A healthy balance of vaginal microflora is essential during pregnancy. The microflora influences the risk of preterm birth and other complications. Lactobacilli, in particular, have been associated with a lower risk of preterm birth, highlighting their role in supporting reproductive health.

• Influence of Menstrual Cycle:The composition of the vaginal microflora can vary throughout the menstrual cycle. Hormonal fluctuations impact the environment, and the microbial community adapts accordingly. Understanding these cyclical changes is crucial for comprehending the dynamic nature of vaginal health.

• Challenges to Vaginal Microflora:Several factors can disrupt the delicate balance of the vaginal microflora, leading to conditions like bacterial vaginosis or yeast infections. These factors include antibiotic use, hormonal changes, sexual activity, and the use of certain hygiene products. Maintaining a healthy lifestyle and making informed choices can contribute to the preservation of optimal vaginal health.

Conclusion:
The importance of vaginal microflora cannot be overstated, as it plays a multifaceted role in maintaining the health and functionality of the female reproductive system. From creating a protective barrier against infections to influencing hormonal regulation and immune responses, the diverse microbial community within the vagina contributes to overall well-being. Understanding the roles of different microbes within this ecosystem is crucial for advancing knowledge in women's health and developing targeted interventions to support and preserve the delicate balance of the vaginal microflora.

 

 

The connection between high-absorbency dry tampons and Toxic Shock Syndrome (TSS)

The connection between high-absorbency dry tampons and Toxic Shock Syndrome (TSS) has been a significant area of research since the 1980s, following several highly publicised cases of TSS linked to tampon use. TSS is a rare but life-threatening condition caused by bacterial infections, often involving Staphylococcus aureus or Streptococcus pyogenes.

Here are key research findings and areas of study that have explored the connection:

• Role of Tampon Composition in TSS:
• Super absorbent Tampons and TSS Outbreaks (1980s) Early research in the 1980s, particularly around products like Rely tampons, found that tampons with higher absorbency made of synthetic materials (like polyester, polyacrylate, and carboxymethylcellulose) were associated with a higher incidence of TSS. The enhanced absorbency seemed to create an environment that fostered bacterial growth, especially Staphylococcus aureus, which produces toxic shock syndrome toxin-1 (TSST-1).

Shands et al. (1980), published in The New England Journal of Medicine, linked super absorbent tampons with increased TSS incidence. The high-absorbency materials seemed to increase vaginal dryness and micro tears, which facilitated bacterial colonisation.

• Tampon Absorbency and Vaginal Dryness:
• Micro trauma and Mucosal Integrity: Research has shown that high-absorbency tampons can cause vaginal dryness and microtears in the mucosal lining, which may allow bacteria like S. aureus to penetrate the tissues, leading to infection. Vaginal mucosal damage was demonstrated in studies such as those by Kass et al. (1984), which showed that dry tampons increased the likelihood of TSS because of the vaginal environment changes.

• Impact of Dryness on Bacterial Proliferation:
• Dry tampons, especially those left in the body for extended periods, create a less moist environment, which may paradoxically increase bacterial production of TSST-1 by promoting oxygen exposure (oxygen levels are believed to influence toxin production).

• Absorbency Levels and Risk of TSS
• Absorbency Levels and TSS Incidence (CDC): A Centers for Disease Control and Prevention (CDC) study in the early 1980s found a direct correlation between tampon absorbency levels and the incidence of TSS. Women who used high-absorbency tampons were at a higher risk of developing the syndrome. Tampons that absorbed more blood also seemed to deplete moisture from the vaginal canal, leading to a drier environment conducive to bacterial growth.

• Proctor & Gamble Study (1981):
• Following several cases of TSS linked to their superabsorbent Rely tampons, Proctor & Gamble conducted internal studies to investigate the relationship between absorbency and bacterial growth. The results confirmed that superabsorbent tampons increased the risk of bacterial proliferation.

• Toxin Production (TSST-1):
• Researchers like Schlievert et al. (1981) identified TSST-1 as the main toxin responsible for TSS in tampon users. High-absorbency tampons created an aerobic environment in the vaginal canal, which promoted the growth of S. aureus and the production of TSST-1. Studies confirmed that the release of the toxin into the bloodstream led to the severe symptoms of TSS.

• Vaginal pH and Microbiota Disruption:
• Tampons with high absorbency may also alter the vaginal pH and microbiome, disrupting the natural balance and facilitating bacterial growth. Research by Farage et al. (2004) found that changes in vaginal flora due to tampon use could contribute to increased risk of infection.

• Post-1980s Safety Regulations and Product Design:
• FDA Regulations:
• After the widespread concern over tampons and TSS, the FDA introduced regulations on tampon absorbency labeling and guidelines for safer use. Studies that followed, like those conducted by Leyden et al. (1991), evaluated the effects of these regulatory changes, finding a decrease in TSS cases following the withdrawal of superabsorbent products and the introduction of clear absorbency guidelines.

• New Tampon Designs and TSS Risk:
• Further research has explored how modern tampon designs (e.g., reduced absorbency or use of cotton fibers) have minimized the risk of TSS. Studies like those from Vostral (2008) discuss how design changes aimed to address the microbiological risks identified in earlier research.

 

Continued Vigilance and Education

• Educational Campaigns and Public Awareness:
• Public health campaigns initiated in the 1980s and 1990s have played a crucial role in educating women about the risks of TSS and the importance of changing tampons frequently, using lower absorbency products when possible, and alternating with pads. Studies have found that these educational efforts have contributed to a decline in tampon-associated TSS.

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Overall, the body of research on tampons and TSS shows a clear link between high-absorbency synthetic tampons and an increased risk of TSS. Since the 1980s, tampon composition and absorbency levels have been adjusted, resulting in a significant reduction in cases, though vigilance in product use and further research on microbiome impacts remain important.